1616617-68-5Relevant academic research and scientific papers
Synthesis of benzofuro[2,3-c]pyridines via a one-pot three-component reaction
Hu, Jiaxing,Deng, Zhihong,Zhang, Xueqiong,Zhang, Fanglin,Zheng, Hua
, p. 4885 - 4889 (2014/07/07)
A convenient one-pot reaction was conducted by mixing bromoacetophenone, a functionalized α,β-unsaturated ketone and potassium hydroxide in tetrahydrofuran at room temperature, ammonium acetate was added and heated to reflux, resulting in four chemical bonds forming from easily accessible substrates. This process provides a flexible and rapid synthetic route for the construction of polysubstituted benzofuro[2,3-c]pyridines in moderate to good yields. This journal is the Partner Organisations 2014.
