161670-50-4Relevant academic research and scientific papers
Condensation reactions in water of active methylene compounds with arylaldehydes. One-pot synthesis of flavonols
Fringuelli, Francesco,Pani, Giosanna,Piermatti, Oriana,Pizzo, Ferdinando
, p. 11499 - 11508 (1994)
The condensation reactions of acetophenone, cyclohexanone, isophorone, phenylacetonitrile, p-nitrophenylacetonitrile, (phenylsulfonyl)acetonitrile and indene with benzaldehyde were studied in water heterogeneous phase in the presence and absence of anionic and cationic surfactants such as SLS, CTACl, (CTA)2SO4 and CTAOH. All the reactions occur with excellent yields. The cationic surfactants favour the reaction and the comparison with the corresponding tetrabutylammonium salts show that the micellar catalysis is effective mainly towards the dehydration reaction following that of condensation. Anionic surfactant SLS is inactive. 2'-hydroxychalcones were prepared in aqueous medium in good-excellent yields and the one-pot synthesis of 7- and 3',4'-substituted flavonols was achieved.
Synthesis of 1,2-diazaphenalenes under microwave
El Barkaoui, Yousri,Jorio, Noura,Fkih-Tétouani, Souad,El Louzi, Ahmed,Loupy, André
, p. 1517 - 1525 (2007/10/03)
1,2-Diazaphenalenes were prepared by condensation reactions of hydrazine with isophorone derivatives under various conditions: conventional heating in homogeneous solution and microwave activation either in homogeneous solution or in dry media. Microwave
