1616883-08-9Relevant academic research and scientific papers
Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors
Grover, Jagdeep,Kumar, Vivek,Sobhia, M. Elizabeth,Jachak, Sanjay M.
, p. 4638 - 4642 (2015/01/09)
As a part of our continued efforts to discover new COX inhibitors, a series of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones were synthesized and evaluated for in vitro COX inhibitory potential. Within this series, seven compounds (3a-d, 3h, 3k and 3
Potassium carbonate-mediated efficient and convenient synthesis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1 H)-ones
Grover, Jagdeep,Roy, Somendu Kumar,Jachak, Sanjay Madhukar
, p. 1914 - 1923 (2014/07/07)
Unprecedented cyclization was observed during N-sulfonylation of 3-[1-(phenylhydrazono)-ethyl]-chromen-2-one in pyridine, affording 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones. To avoid use of noxious pyridine, reaction was tried in different basic
