1616976-29-4Relevant academic research and scientific papers
The sila-Pummerer reaction of γ-silyl substituted cycloalkanoyl sulfoxides: The first examples and a new approach to 3-substituted cycloalk-2-enones
Mikina, Maciej,Miko?ajczyk, Marian
, p. 3954 - 3956 (2014/07/08)
The thermal decomposition of 3-(α-trimethylsilyl)alkyl substituted 2-(phenylsulfinyl)cycloalkanones occurs via the γ-sila-Pummerer reaction, affording 3-substituted cycloalk-2-enones and unstable trimethylsilyl benzenesulfenate as an elimination by-product. The starting γ-silyl substituted cycloalkanoyl sulfoxides were obtained through the conjugate addition reaction of nucleophilic reagents to 2-(phenylsulfinyl)cycloalk-2- enones. The tandem conjugate addition/γ-sila-Pummerer reaction investigated here provides a new route to 3-substituted cycloalk-2-enones.
