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16175-04-5

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16175-04-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 16175-04-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,7 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16175-04:
(7*1)+(6*6)+(5*1)+(4*7)+(3*5)+(2*0)+(1*4)=95
95 % 10 = 5
So 16175-04-5 is a valid CAS Registry Number.

16175-04-5Relevant articles and documents

DIHYDROBENZO[B][1]BENZOTHIEPIN COMPOUNDS USEFUL IN THERAPY

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Page/Page column 29; 30; 31; 32; 38, (2019/05/30)

The present invention relates to the use of a compound of formula (I), to decrease or inhibit, in vitro or ex vivo, the Patched receptor drug efflux activity, in particular the chemotherapeutic drug efflux activity and chemotherapy resistance. The present disclosure further relates to uses of such compounds, in particular to prepare a pharmaceutical composition to allow or improve the efficiency of a therapy of cancer in a subject in need thereof. The compound of the invention can indeed be advantageously used, in combination with at least one chemotherapeutic drug, for treating cancer, for preventing cancer metastasis and/or for preventing cancer recurrence in a subject.

Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors

Nuti, Elisa,Panelli, Laura,Casalini, Francesca,Avramova, Stanislava I.,Orlandini, Elisabetta,Santamaria, Salvatore,Nencetti, Susanna,Tuccinardi, Tiziano,Martinelli, Adriano,Cercignani, Giovanni,D'Amelio, Nicola,Maiocchi, Alessandro,Uggeri, Fulvio,Rossello, Armando

experimental part, p. 6347 - 6361 (2010/03/24)

Overexpression of macrophage elastase (MMP-12), a member of the matrix metalloproteinases family, can be linked to tissue remodeling and degradation in some inflammatory processes, such as chronic obstructive pulmonary disease (COPD), emphysema, rheumatoi

Derivatives of hydroxyphenylsulfanylbenzoic and hydroxphenylsulfanylarylacetic acids

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, (2008/06/13)

Processes for the preparation of derivatives of hydroxyphenylsulfanylbenzoic and hydroxyphenylsulfanylarylacetic acids of Formula (I) and pharmaceutical compositions including these compounds are provided: wherein X is H, halogen or NO2group, n is 0 or 1, and m is 2 to 4 if Z is either 4-acetyl-3 -hydroxy-2-propylphenoxy of Formula (II): or a piperazinyl residue, or m is 1 if Z is quinolin-2-yl or 6-chloroquinoli-2-yl.

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