19862-91-0Relevant articles and documents
Polymer-bound chiroptical molecular switches; photochemical modification of the chirality of thin films
Oosterling, Michiel L.C.M.,Schoevaars, Anne Marie,Haitjema, Henk J.,Feringa, Ben L.
, p. 341 - 348 (1996)
Photobistable chiral polymers were obtained by covalent attachment of inherently dissymmetric 2-hydroxy-9-(7′methyl-1′,2′,3′,4′- tetrahydrophenanthrene-4′-ylidene)-9H-thioxanthene to methacrylate copolymers with appropriate spacers. Upon irradiation at 300 nm the optical activity of thin films of these polymers could be altered.
Transition-metal-free synthesis of unsymmetrical diaryl chalcogenides from arenes and diaryl dichalcogenides
Prasad, Ch Durga,Balkrishna, Shah Jaimin,Kumar, Amit,Bhakuni, Bhagat Singh,Shrimali, Kaustubh,Biswas, Soumava,Kumar, Sangit
, p. 1434 - 1443 (2013/03/29)
A transition-metal-free synthetic method has been developed for the synthesis of unsymmetrical diaryl chalcogenides (S, Se, and Te) from diaryl dichalcogenides and arenes under oxidative conditions by using potassium persulfate at room temperature. Variously substituted arenes such as anisole, thioanisole, diphenyl ether, phenol, naphthol, di- and trimethoxy benzenes, xylene, mesitylene, N,N-dimethylaniline, bromine-substituted arenes, naphthalene, and diaryl dichalcogenides underwent carbon-chalcogen bond-forming reaction to give unsymmetrical diaryl chalcogenides in trifluoroacetic acid. To understand the mechanistic part of the reaction, a detailed in situ characterization of the intermediates has been carried out by 77Se NMR spectroscopy by using diphenyl diselenide as the substrate. 77Se NMR study suggests that electrophilic species ArE+ is generated by the reaction of diaryl dichalcogenide with persulfate in trifluoroacetic acid. The electrophilic attack of arylchalcogenium ion on the arene may be responsible for the formation of the aryl-chalcogen bond.
Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors
Nuti, Elisa,Panelli, Laura,Casalini, Francesca,Avramova, Stanislava I.,Orlandini, Elisabetta,Santamaria, Salvatore,Nencetti, Susanna,Tuccinardi, Tiziano,Martinelli, Adriano,Cercignani, Giovanni,D'Amelio, Nicola,Maiocchi, Alessandro,Uggeri, Fulvio,Rossello, Armando
experimental part, p. 6347 - 6361 (2010/03/24)
Overexpression of macrophage elastase (MMP-12), a member of the matrix metalloproteinases family, can be linked to tissue remodeling and degradation in some inflammatory processes, such as chronic obstructive pulmonary disease (COPD), emphysema, rheumatoi
