1617506-03-2Relevant articles and documents
Inhibition of 17β-HSD1: SAR of bicyclic substituted hydroxyphenylmethanones and discovery of new potent inhibitors with thioether linker
Abdelsamie, Ahmed S.,Bey, Emmanuel,Hanke, Nina,Empting, Martin,Hartmann, Rolf W.,Frotscher, Martin
, p. 394 - 406 (2014/07/07)
Estradiol is the most potent estrogen in humans. It is known to be involved in the development and proliferation of estrogen dependent diseases such as breast cancer and endometriosis. The last step of its biosynthesis is catalyzed by 17β-hydroxysteroid d