161759-99-5 Usage
Uses
Used in Pharmaceutical Industry:
2,3,4,5,6-PENTAFLUOROPHENYL 4-CHLOROBENZENESULPHONATE is used as a reagent for the synthesis of various drugs and pharmaceutical intermediates. Its role in introducing the pentafluorophenylsulfonyl protecting group is crucial in the development of new medications, enhancing the efficiency and effectiveness of drug production processes.
Used in Agrochemical Production:
In the agrochemical industry, 2,3,4,5,6-PENTAFLUOROPHENYL 4-CHLOROBENZENESULPHONATE is used as a building block in the production of various agrochemicals. Its chemical properties contribute to the creation of compounds that can be used in pest control and crop protection, ensuring agricultural productivity and food security.
Used in Advanced Materials:
2,3,4,5,6-PENTAFLUOROPHENYL 4-CHLOROBENZENESULPHONATE is also utilized in the development of advanced materials, where its chemical stability and reactivity are essential for creating innovative products with unique properties. These materials can be found in various applications, such as electronics, aerospace, and renewable energy technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 161759-99-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,7,5 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 161759-99:
(8*1)+(7*6)+(6*1)+(5*7)+(4*5)+(3*9)+(2*9)+(1*9)=165
165 % 10 = 5
So 161759-99-5 is a valid CAS Registry Number.
161759-99-5Relevant articles and documents
One-Pot Synthesis of Pentafluorophenyl Sulfonic Esters via Copper-Catalyzed Reaction of Aryl Diazonium Salts, DABSO, and Pentafluorophenol
Idris, Muhammad Aliyu,Lee, Sunwoo
supporting information, p. 4516 - 4520 (2021/05/26)
Pentafluorophenyl (PFP) sulfonic esters were synthesized via a copper-catalyzed one-pot multicomponent reaction of aryl diazonium tetrafluoroborate, DABSO (DABCO·(SO2)2), and pentafluorophenol. The reaction system provided the desired pentafluorophenyl sulfonic esters in good yields and exhibited excellent functional group tolerance. In addition, the generated PFP sulfonic esters were successfully applied in Sonogashira, Suzuki, Chan-Evans-Lam, and decarboxylative coupling reactions.
Copper-Catalyzed Synthesis of Activated Sulfonate Esters from Boronic Acids, DABSO, and Pentafluorophenol
Vedovato, Vincent,Talbot, Eric P. A.,Willis, Michael C.
supporting information, p. 5493 - 5496 (2018/09/12)
The synthesis of pentafluorophenyl (PFP) sulfonate esters based on the Pd-catalyzed sulfination of aryl and heteroaryl boronic acids is reported. The sulfinate intermediates are converted in situ to the corresponding sulfonate esters using a copper-catalyzed oxidative process, providing a broad range of PFP esters in good yields.
