1618-64-0 Usage
General Description
1-[3-(trifluoromethyl)phenyl]-2H-3,1-benzoxazine-2,4(1H)-dione is a chemical compound that falls under the category of benzoxazine derivatives. It is characterized by a trifluoromethyl group attached to a phenyl ring, as well as a 2,4-dioxo-1,3-benzoxazine core structure. 1-[3-(trifluoromethyl)phenyl]-2H-3,1-benzoxazine-2,4(1H)-dione has potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science. Its unique structure and properties make it useful in the synthesis of new drugs, pesticides, and advanced materials. Additionally, its trifluoromethyl group contributes to its distinct chemical and physical properties, making it a valuable building block for further chemical transformations and developments.
Check Digit Verification of cas no
The CAS Registry Mumber 1618-64-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,1 and 8 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1618-64:
(6*1)+(5*6)+(4*1)+(3*8)+(2*6)+(1*4)=80
80 % 10 = 0
So 1618-64-0 is a valid CAS Registry Number.
1618-64-0Relevant articles and documents
Synthesis and antiinflammatory activity of certain new 1,2,3-triaryl-2,3-dihydro-4(1H)-quinazolinones
Gineinah,Abdelal,Nasr,Said
, p. 17 - 28 (2007/10/02)
A series of 1,2,3-triaryl-2,3-dihydro-4(1H)-quinazolinones, 4a-e, 5a-e, 6a-e, 7a-e, 8a-d and 9a-d was prepared. The structures of the prepared compound were established from their analytical data, IR spectra, 1H-NMR and mass spectroscopy. Compounds 4a, 4b, 4c, 5b, 5c, 5d, 6a, 6b, 6d, 7a, 7b, 7c, 8a, 8b, 8c, 9a and 9b were tested for antiinflammatory activity in the rat paw edema test. The results revealed that compounds 9b, 9a, 7a and 7b produced significant antiinflammatory activity at a dose of 100 mg/kg, i.e., about 30-70% inhibition of edema. Whereas, flufenamic acid at a dose of 10 mg/kg caused 70% inhibition.