1618-98-0

Basic information

• Product Name: (3S)-3aβ,4,5,6,6aβ,9bα-Hexahydro-3,6,9-trimethyl-6β-hydroxyazuleno[4,5-b]furan-2,8(3H,7H)-dione
• Synonyms: (3S)-3aβ,4,5,6,6aβ,9bα-Hexahydro-3,6,9-trimethyl-6β-hydroxyazuleno[4,5-b]furan-2,8(3H,7H)-dione;(3S,3aβ,6aβ,9bα)-3a,5,6,6a,7,9b-Hexahydro-6β-hydroxy-3β,6,9-trimethylazuleno[4,5-b]furan-2,8(3H,4H)-dione;(αS,4S)-α,3,8α-Trimethyl-2-oxo-4β,8-dihydroxy-1,2,4,5,6,7,8,8aβ-octahydroazulene-5α-acetic acid 5,4-lactone;3aβ,5,6,6aβ,7,9bα-Hexahydro-6β-hydroxy-3β,6,9-trimethylazuleno[4,5-b]furan-2,8(3H,4H)-dione
• CAS NO: 1618-98-0
• Molecular Formula: C₁₅H₂₀O₄
• Molecular Weight: 264.3169
• Mol File: 1618-98-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3S)-3aβ,4,5,6,6aβ,9bα-Hexahydro-3,6,9-trimethyl-6β-hydroxyazuleno[4,5-b]furan-2,8(3H,7H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-3aβ,4,5,6,6aβ,9bα-Hexahydro-3,6,9-trimethyl-6β-hydroxyazuleno[4,5-b]furan-2,8(3H,7H)-dione(1618-98-0)
• EPA Substance Registry System: (3S)-3aβ,4,5,6,6aβ,9bα-Hexahydro-3,6,9-trimethyl-6β-hydroxyazuleno[4,5-b]furan-2,8(3H,7H)-dione(1618-98-0)

Safety Data

• Hazardous Substances Data: 1618-98-0(Hazardous Substances Data)

Usage

General Description

The chemical (3S)-3aβ,4,5,6,6aβ,9bα-Hexahydro-3,6,9-trimethyl-6β-hydroxyazuleno[4,5-b]furan-2,8(3H,7H)-dione is a complex organic compound with a unique chemical structure. It is a furanocoumarin, belonging to a class of organic compounds known for their potential biological and pharmaceutical activities. This specific compound is characterized by its bicyclic structure containing a furan ring and a lactone ring, as well as several methyl and hydroxyl groups. Its molecular configuration and functional groups give it potential antioxidant, anti-inflammatory, and antimicrobial properties. The compound may also have applications in the pharmaceutical and cosmetic industries due to its unique structural features and potential biological activities.

Upstream product

• 481-06-1 santonin 
• 74501-23-8 10α-acetoxy-1,7α,5,6,11βH-guaia-3-en-6,12-olide 
• 7759-23-1 O-acetylisophotosantonic lactone 
• 467-41-4 (3aS)-3c,6,6a-trimethyl-(3ar,6at,9bt)-3a,4,5,6,6a,9b-hexahydro-3H-6c,9ac-cyclo-azuleno[4,5-b]furan-2,7-dione 

Downstream Products

• 1373334-12-3 C₂₅H₃₄O₅Si 
• 50299-47-3 (6R)-6-hydroxydichotoma-3,14-diene-1,17-dial 
• 67310-22-9 Toluene-4-sulfonic acid (S)-2-((3aS,4S,5S,8aR)-3-methyl-8-methylene-4-trimethylsilanyloxy-1,3a,4,5,6,7,8,8a-octahydro-azulen-5-yl)-propyl ester 

Relevant articles and documents

Facile preparation of bioactive seco-Guaianolides and Guaianolides from Artemisia gorgonum and evaluation of their phytotoxicity

Commercially available santonin was used to synthesize seven sesquiterpene lactones using a facile strategy that involved a high-yielding photochemical reaction. Three natural products from Artemisia gorgonum were synthesized in good yields, and in the case of two compounds, absolute configurations were determined from X-ray quality crystals. The structures previously reported for these compounds were revised. Sesquiterpene lactones were tested using the etiolated wheat coleoptile bioassay, and the most active compounds were assayed in standard target species. seco-Guaianolide (4) showed higher phytotoxic activities than the known herbicide Logran. This high activity could be due to the presence of a cyclopentenedione ring. These results suggest that compound 4 should be involved in defense of A. gorgorum, displaying a wide range of activities that allow proposing them as new leads for development of a natural herbicide model with a seco-guaianolide skeleton.

Synthetic studies on arglabin diene; An alleged precursor to arteminolides

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