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Lumisantonin, also known as 2,3-dihydro-2-(4-hydroxyphenyl)-3-(2-methyl-1H-indol-3-yl)-4H-benzo[d][1,3]oxazine, is a naturally occurring chemical compound found in the plant species Sanguinaria canadensis, commonly known as bloodroot. It is a benzoxazine alkaloid with a molecular formula of C20H17NO2 and a molecular weight of 303.35 g/mol. Lumisantonin exhibits various biological activities, including anti-inflammatory, antimicrobial, and anticancer properties. It has been studied for its potential therapeutic applications, particularly in the treatment of cancer, due to its ability to inhibit the activity of certain enzymes and disrupt cell cycle progression. However, further research is needed to fully understand its mechanisms of action and potential side effects.

467-41-4

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467-41-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 467-41-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 7 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 467-41:
(5*4)+(4*6)+(3*7)+(2*4)+(1*1)=74
74 % 10 = 4
So 467-41-4 is a valid CAS Registry Number.

467-41-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Lumisantonin

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:467-41-4 SDS

467-41-4Relevant academic research and scientific papers

Synthesis and cytotoxic activity of α-santonin derivatives

Arantes, Francisco F.P.,Barbosa, Luiz C.A.,Alvarenga, Elson S.,Demuner, Antonio J.,Bezerra, Daniel P.,Ferreira, Jose R.O.,Costa-Lotufo, Leticia V.,Pessoa, Claudia,Moraes, Manoel O.

, p. 3739 - 3745 (2009)

Ten α-santonin derivatives were synthesized in moderate to high yields. Four derivatives namely 10α-acetoxy-3-oxo-1,7αH,6,11βH-guai-4-en-6,12-olide (2), isofotosantonic acid (3), 10α-hydroxy-3-oxo-1,7αH,6,11βH-guai-4-en-6,12-olide (4), and lumisantonin (5

A photocatalyzed aliphatic fluorination

Bloom, Steven,Knippel, James Levi,Lectka, Thomas

, p. 1175 - 1178 (2014/03/21)

We disclose a new approach to the catalysis of alkane fluorination employing ultraviolet light and a photosensitizer, 1,2,4,5-tetracyanobenzene (TCB). The process is efficient, mild, and operationally straightforward. We demonstrate reaction utility on a variety of substrates, from simple hydrocarbons to complex natural products. In a showcase example, we establish that the well-known photochemical rearrangement of α-santonin can be supplanted by a highly selective catalyzed fluorination. The Royal Society of Chemistry 2014.

Transformation of α-Santonin to Lumisantonin by Pseudomonas cichorii S

Naik, U. P.,Paknikar, S. K.,Mavinkurve, S.

, p. 501 (2007/10/02)

Lumisantonin (2) has been identified as one of the transformation products of α-santonin (1) by Pseudomonas cichorii S.

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