161803-04-9

Basic information

• Product Name: 4-(tert-butyl(diphenyl)silanyloxymethyl)-phenylamine
• Synonyms: 4-(tert-butyl(diphenyl)silanyloxymethyl)-phenylamine
• CAS NO: 161803-04-9
• Molecular Weight: 361.559
• Mol File: 161803-04-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-(tert-butyl(diphenyl)silanyloxymethyl)-phenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(tert-butyl(diphenyl)silanyloxymethyl)-phenylamine(161803-04-9)
• EPA Substance Registry System: 4-(tert-butyl(diphenyl)silanyloxymethyl)-phenylamine(161803-04-9)

Safety Data

• Hazardous Substances Data: 161803-04-9(Hazardous Substances Data)

Upstream product

• 623-04-1 4-aminobenzenemethanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 161803-03-8 1-nitro-4-(tert-butyldiphenylsiloxymethyl)benzene 
• 619-73-8 4-nitrobenzyl chloride 
• 104-10-9 2-(4'-aminophenyl)ethyl alcohol 

Downstream Products

• 113068-95-4 tert-butyldiphenylsilyl 4-oxymethylphenyl isocyanate 
• 161803-05-0 di-tert-butyl N-<(4-<oxymethyl>phenyl)carbamoyl>-L-glutamate 
• 161803-06-1 di-tert-butyl N-<(4-phenyl)carbamoyl>-L-glutamate 
• 1469894-70-9 7-(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-5-hydroxy-4-oxo-4H-chromen-3-yl 7-(2-(4-(tert-butyldiphenylsilyloxy)phenylamino)-2-oxoethylamino)-7-oxoheptanoate 
• 1469894-67-4 2-amino-N-(4-((tert-butyldiphenylsilyloxy)methyl)phenyl)acetamide 

Relevant articles and documents

Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif

The ability of three different bifunctional azobenzene linkers to enable the photoreversible formation of a defined intermolecular two-tetrad G-quadruplex upon UV/Vis irradiation was investigated. Circular dichroism and NMR spectroscopic data showed the formation of G-quadruplexes with K+ ions at room temperature in all three cases with the corresponding azobenzene linker in an E conformation. However, only the para-para-substituted azobenzene derivative enables photoswitching between a nonpolymorphic, stacked, tetramolecular G-quadruplex and an unstructured state after E-Z isomerization.

Prodrugs of protein tyrosine kinase inhibitors

A compound which comprises a prodrug of a protein tyrosine kinase inhibitor (PTKi) linked to a protecting group which is capable of being cleaved from the compound to release the PTKi, said PTKi prodrugs including tyrphostins, of formula (I), STR1 where X

Improvements relating to prodrugs

A prodrug of the general formula FTLi-(PRT)m, where m is an integer from 1 to 5; FTLi is a ras inhibitor such as a farnesyltransferase inhibitor compound, such as Ia, Ib, Ic; and PRT represents m protecting groups or a precursor thereof, such as compound