161824-75-5

Basic information

• Product Name: (1aR,2R,7bS)-2-Ethynyl-7b-(1-hydroxy-1-methyl-ethyl)-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester
• Synonyms: (1aR,2R,7bS)-2-Ethynyl-7b-(1-hydroxy-1-methyl-ethyl)-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester
• CAS NO: 161824-75-5
• Molecular Weight: 349.386
• Mol File: 161824-75-5.mol

Chemical Properties

• CAS DataBase Reference: (1aR,2R,7bS)-2-Ethynyl-7b-(1-hydroxy-1-methyl-ethyl)-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1aR,2R,7bS)-2-Ethynyl-7b-(1-hydroxy-1-methyl-ethyl)-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester(161824-75-5)
• EPA Substance Registry System: (1aR,2R,7bS)-2-Ethynyl-7b-(1-hydroxy-1-methyl-ethyl)-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester(161824-75-5)

Safety Data

• Hazardous Substances Data: 161824-75-5(Hazardous Substances Data)

Upstream product

• 161907-03-5 (S)-4-[(R)-1-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2-trimethylsilanylethynyl-2H-quinoline-1-carboxylic acid phenyl ester 
• 169103-38-2 (1aR,2R,7bR)-2-Ethynyl-7b-((R)-1-hydroxy-ethyl)-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester 
• 161907-02-4 4-[(R)-1-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-quinoline 
• 161824-80-2 (S)-2-Ethynyl-4-((R)-1-hydroxy-ethyl)-2H-quinoline-1-carboxylic acid phenyl ester 
• 161907-07-9 (R)-1-(4-quinolyl)ethanol 
• 161824-74-4 Acetic acid (R)-1-quinolin-4-yl-ethyl ester 
• 1885-14-9 phenyl chloroformate 
• 75-16-1 methylmagnesium bromide 
• 161907-04-6 (1aR,2R,7bS)-7b-Acetyl-2-ethynyl-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester 

Downstream Products

• 161824-76-6 (2R,3S,4S)-4-Acetyl-2-ethynyl-3-hydroxy-4-methyl-3,4-dihydro-2H-quinoline-1-carboxylic acid phenyl ester 

Relevant articles and documents

Synthesis and Biological Evaluation of Both Enantiomers of Dynemicin A Model Compound

A novel 1,4-asymmetric induction was developed for the synthesis of chiral dynemicin A model compound.By using this reaction, both enantiomers were synthesized from chiral alcohol prepared by lipase catalyzed resolution.The biological activities of these compounds were examined.

Synthesis of both enantiomers of dynemicin A model compound. New remote asymmetric induction in acetylide addition into quinoline nucleus as key step

A new and highly selective 1,4-asymmetric induction in the addition of magnesium acetylide into quinoline nucleus was developed. By using this reaction, both enantiomers of dynemicin A model compound were synthesized from chiral alcohol which was prepared