16183-35-0

Basic information

• Product Name: N-(3-CHLOROBENZYL)BUTAN-1-AMINE
• Synonyms: CHEMBRDG-BB 9071982;N-(3-CHLOROBENZYL)BUTAN-1-AMINE;AKOS LT-1098X1398;N-(3-CHLOROBENZYL)-1-BUTANAMINE;N-(3-CHLOROPHENYLMETHYL)BUTYLAMINE;UKRORGSYN-BB BBV-125639;N-(3-chlorobenzyl)-1-butanamine(SALTDATA: HCl);N-(3-chlorobenzyl)-1-butanamine 1HCl
• CAS NO: 16183-35-0
• Molecular Formula: C11H16ClN
• Molecular Weight: 197.7
• Mol File: 16183-35-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 264.2°Cat760mmHg
• Flash Point: 113.6°C
• Appearance: /
• Density: 1.026g/cm³
• Vapor Pressure: 0.00984mmHg at 25°C
• Refractive Index: 1.516
• PKA: 9.44±0.19(Predicted)
• CAS DataBase Reference: N-(3-CHLOROBENZYL)BUTAN-1-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-CHLOROBENZYL)BUTAN-1-AMINE(16183-35-0)
• EPA Substance Registry System: N-(3-CHLOROBENZYL)BUTAN-1-AMINE(16183-35-0)

Safety Data

• Hazardous Substances Data: 16183-35-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H16ClN/c1-2-3-7-13-9-10-5-4-6-11(12)8-10/h4-6,8,13H,2-3,7,9H2,1H3

Upstream product

• 109-73-9 N-butylamine 
• 766-80-3 1-bromomethyl-3-chlorobenzene 

Relevant articles and documents

SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS

Disclosed are compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein: W and Q and G are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bcl-2 family antiapoptotic proteins for the treatment of cancer; and pharmaceutical compositions comprising such compounds.

EFFECTS OF SUBSTITUENTS IN THE BENZYL BROMIDE ON THE KINETICS OF THE BENZYLATION OF AMINES

The kinetics of the reactions of 3- and 4-substituted benzyl bromides with amines having various structures in nitrobenzene at 40 deg C were investigated.The 4-substituted benzyl bromides have higher reactivity compared with that calculated on the basis of the linear correlations according to the Hammett-Taft equation for unsubstituted and 3-substituted benzyl bromides containing electron-withdrawning substituents.The reactivity of benzyl bromides containing electron-donating substituents obeys a linear correlation with the ?+ constants.The effects of structural changes in the substrate and the nucleophile on the character of the transition states of the investigated reactions is discussed.