161838-71-7

Upstream product

• 1026896-06-9 (2R)-2-<(4R)-2,2-dimethyl-1,3-dioxolan-4-yl>-1-(4-nitrobenzoyloxy)pent-4-ene 
• 161838-68-2 (R)-4-((S)-1-Bromomethyl-but-3-enyl)-2,2-dimethyl-[1,3]dioxolane 
• 130432-70-1 (2R,3R)-3-(benzyloxymethyl)-1-benzyloxyhex-5-en-2-ol 
• 130432-75-6 (5R,4R)-5-<(tert-butyldimethylsilyloxy)methyl>-4-(prop-2-en-1-yl)oxolan-2-one 
• 130432-76-7 (5R,4R)-5-<(tert-butyldimethylsilyloxy)methyl>-4-(prop-2-en-1-yl)-2-oxolene 
• 130432-73-4 (2R)-2-<(4R)-2,2-dimethyl-1,3-dioxolan-4-yl>-1-cyanopent-4-ene 
• 130432-72-3 (2R)-2-<(4R)-2,2-dimethyl-1,3-dioxolan-4-yl>pent-4-en-1-ol 
• 130432-74-5 (5R,4R)-5-(hydroxymethyl)-4-(prop-2-en-1-yl)oxolan-2-one 
• 130432-71-2 (2R,3R)-3-(hydroxymethyl)hex-5-en-1,2-diol 
• 100-39-0 benzyl bromide 
• 161838-70-6 (E)-(2S,6R)-2,4-dimethyl-6-<(5R)-2,2-dimethyl-1,3-dioxolan-4-yl>non-4,8-dien-1-ol 
• 161838-69-3 (E)-(2R,3R,7S)-8-(methoxymethoxy)-5,7-dimethyl-3-(prop-2-en-1-yl-)-1-(tert-butyldimethylsilyloxy)oct-4-en-2-ol 

Downstream Products

• 161838-72-8 (E)-(2R,3R,7S)-8-benzyloxy-5,7-dimethyl-3-(prop-2-en-1-yl)oct-4-ene-1,2-diol 

Relevant academic research and scientific papers

Synthesis of the C16-C23 effector domain of FK-506 via copper-catalysed metallate rearrangement of an α-alkoxyalkenylcuprate

A 1,2-metallate rearrangement of the putative higher order cuprate 17 derived from reaction of the metallated dihydrofuran 15 with the homocuprate 16 occurred with clean inversion of configuration to give the alkenylcuprate 18. Methylation of 18 followed