161859-44-5

Basic information

• Product Name: L-(N-hexadecanoyl)-thiazolidine-4-carboxylic acid ethyl ester
• Synonyms: L-(N-hexadecanoyl)-thiazolidine-4-carboxylic acid ethyl ester
• CAS NO: 161859-44-5
• Molecular Weight: 399.638
• Mol File: 161859-44-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-(N-hexadecanoyl)-thiazolidine-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-(N-hexadecanoyl)-thiazolidine-4-carboxylic acid ethyl ester(161859-44-5)
• EPA Substance Registry System: L-(N-hexadecanoyl)-thiazolidine-4-carboxylic acid ethyl ester(161859-44-5)

Safety Data

• Hazardous Substances Data: 161859-44-5(Hazardous Substances Data)

Upstream product

• 86028-91-3 L-thiazolidine-4-carboxylic acid ethyl ester hydrochloride 
• 112-67-4 n-hexadecanoyl chloride 

Relevant articles and documents

Synthesis of heterocyclic platelet activating factor analogues

The synthesis of heterocyclic analogues of the platelet activating factor is described.The preparation starts with acylating rac-tetrahydro-1,3-thiazine-4-carboxylic acid ethyl ester, with palmitoyl chloride to form the amide linkage.Following ester reduction, the phosphocholine part is introduced via 2-chloro-2-oxo-1,3,2-dioxaphospholane and subsequent ring opening with trimethylamine under pressure.Furthermore, the related L-thiazolidine analogue is prepared using the same procedure.In addition the sulfinyl and sulfonyl derivatives of this compound are obtained by oxidation with 3-chloro-perbenzoic acid.From one sulfinyl intermediate the diastereomeres are separated and their conformations are determined by 13C-NMR spectroscopy. Keywords: Phospholipid synthesis; Cyclic platelet activating factor analogue; Cyclic thioether; Chiral sulphur compound