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86028-91-3

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  • China Biggest factory Supply High Quality Ethyl L-thiazolidine-4-carboxylate hydrochloride CAS 86028-91-3

    Cas No: 86028-91-3

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86028-91-3 Usage

General Description

Ethyl L-thiazolidine-4-carboxylate hydrochloride, also known as pioglitazone hydrochloride, is a pharmaceutical compound that belongs to the class of thiazolidinediones. It is commonly used as an oral medication for the treatment of type 2 diabetes mellitus. Pioglitazone hydrochloride works by improving the body's sensitivity to insulin, leading to better control of blood sugar levels. It primarily functions by activating peroxisome proliferator-activated receptor gamma (PPAR-γ) to regulate glucose and lipid metabolism. In addition to its antidiabetic properties, pioglitazone hydrochloride has been found to have potential benefits in reducing inflammation and improving cardiovascular health. However, it is important to note that pioglitazone hydrochloride may also carry certain side effects and should be used under the supervision of a healthcare professional.

Check Digit Verification of cas no

The CAS Registry Mumber 86028-91-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,0,2 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 86028-91:
(7*8)+(6*6)+(5*0)+(4*2)+(3*8)+(2*9)+(1*1)=143
143 % 10 = 3
So 86028-91-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO2S.ClH/c1-2-9-6(8)5-3-10-4-7-5;/h5,7H,2-4H2,1H3;1H

86028-91-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl (4R)-1,3-thiazolidine-4-carboxylate,hydrochloride

1.2 Other means of identification

Product number -
Other names EthylL-thiazolidine-4-carboxylatehydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86028-91-3 SDS

86028-91-3Relevant articles and documents

Synthesis of heterocyclic platelet activating factor analogues

Zeidler, Juergen,Zimmermann, Werner

, p. 73 - 81 (1994)

The synthesis of heterocyclic analogues of the platelet activating factor is described. The preparation starts with acylating rac-tetrahydro-1,3-thiazine-4-carboxylic acid ethyl ester, with palmitoyl chloride to form the amide linkage. Following ester reduction, the phosphocholine part is introduced via 2-chloro-2-oxo-1,3,2-dioxaphospholane and subsequent ring opening with trimethylamine under pressure. Furthermore, the related L-thiazolidine analogue is prepared using the same procedure. In addition the sulfinyl and sulfonyl derivatives of this compound are obtained by oxidation with 3-chloro-perbencoic acid. From one sulfinyl intermediate the diastereomeres are separated and their conformations are determinated by 13C-NMR spectroscopy.

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