161859-48-9

Basic information

• Product Name: L-(N-hexadecanoyl)-thiazolidine-S-dioxide-4-carboxylic acid ethyl ester
• Synonyms: L-(N-hexadecanoyl)-thiazolidine-S-dioxide-4-carboxylic acid ethyl ester
• CAS NO: 161859-48-9
• Molecular Weight: 431.637
• Mol File: 161859-48-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-(N-hexadecanoyl)-thiazolidine-S-dioxide-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-(N-hexadecanoyl)-thiazolidine-S-dioxide-4-carboxylic acid ethyl ester(161859-48-9)
• EPA Substance Registry System: L-(N-hexadecanoyl)-thiazolidine-S-dioxide-4-carboxylic acid ethyl ester(161859-48-9)

Safety Data

• Hazardous Substances Data: 161859-48-9(Hazardous Substances Data)

Upstream product

• 86028-91-3 L-thiazolidine-4-carboxylic acid ethyl ester hydrochloride 

Relevant articles and documents

Synthesis of heterocyclic platelet activating factor analogues

The synthesis of heterocyclic analogues of the platelet activating factor is described. The preparation starts with acylating rac-tetrahydro-1,3-thiazine-4-carboxylic acid ethyl ester, with palmitoyl chloride to form the amide linkage. Following ester reduction, the phosphocholine part is introduced via 2-chloro-2-oxo-1,3,2-dioxaphospholane and subsequent ring opening with trimethylamine under pressure. Furthermore, the related L-thiazolidine analogue is prepared using the same procedure. In addition the sulfinyl and sulfonyl derivatives of this compound are obtained by oxidation with 3-chloro-perbencoic acid. From one sulfinyl intermediate the diastereomeres are separated and their conformations are determinated by 13C-NMR spectroscopy.