1618654-25-3Relevant academic research and scientific papers
An efficient metal-free synthesis of 2-amino-substituted-4(3H)-quinazolinones
Mirza, Behrooz
, p. 146 - 147 (2015/12/23)
2-Amino-substituted-4(3H)-quinazolinones have been synthesized via an efficient metal-free reaction between 2-aminobenzamide derivatives and carbonimidic dibromides. The reaction proceeds in the presence of K2CO3 affording cyclized products in good to excellent yields.
Synthesis of benzoimidazoquinazolines by cobalt-catalyzed isocyanide insertion-cyclization
Ahmadi, Fereshteh,Bazgir, Ayoob
, p. 61955 - 61958 (2016/07/11)
An efficient and practical protocol for the synthesis of benzoimidazoquinazoline amines in moderate to good yields by the reaction of isocyanides and benzo[d]imidazol-anilines via a cobalt-catalyzed isocyanide insertion cyclization reaction into the two N
One-pot synthesis of 2-amino-4(3H)-quinazolinones via ring-opening of isatoic anhydride and palladium-catalyzed oxidative isocyanide-insertion
Ji, Fei,Lv, Mei-Fang,Yi, Wen-Bin,Cai, Chun
, p. 5766 - 5772 (2014/07/22)
An efficient and practical two-step process has been developed for the synthesis of 2-amino-4(3H)-quinazolinones via ring-opening of isatoic anhydride and palladium-catalyzed oxidative isocyanide-insertion in one pot. This regioselective procedure could construct a wide range of 2-amino-4(3H)- quinazolinones in moderate to excellent yields. Furthermore, the methodology also had distinct advantages of easily accessible starting materials and operational simplicity. the Partner Organisations 2014.
