1618679-34-7

Upstream product

• 1618679-31-4 tert-butyl (2S,3R)-3-(benzyloxy)-1-(tert-butyldimethyldimethylsilyloxy)pentan-2-ylcarbamate 
• 1175524-30-7 tert-butyl (2S,3R)-3-(benzyloxy)-1-hydroxypentan-2-ylcarbamate 
• 100-39-0 benzyl bromide 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 1618679-38-1 C₂₁H₃₃NO₅ 
• 1618679-35-8 tert-butyl (4S,5R)-5-(benzyloxy)-1-hydroxyheptan-4-ylcarbamate 
• 1618679-36-9 (S)-tert-butyl 2-((R)-1-(benzyloxy)propyl)pyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

Formal synthesis of (+)-α-conhydrine and stereoselective synthesis of pyrrolidine analogue via the diastereoselective chelation-controlled hydride reduction and wittig reaction

Asymmetric syntheses of (+)-α-conhydrine and its pyrrolidine analogue were achieved from readily available L-serine. The key step involved highly diastereoselective chelation-controlled hydride reduction of the amino ketone to give the anti-amino alcohol