161891-81-2

Basic information

• Product Name: (R)-3-((BENZYLOXY)CARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID
• Synonyms: (R)-3-((BENZYLOXY)CARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID;(S)-3-((BENZYLOXY)CARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID
• CAS NO: 161891-81-2
• Molecular Formula: C₁₄H₁₇NO₅
• Molecular Weight: 279.29
• Mol File: 161891-81-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 447.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.270±0.06 g/cm3(Predicted)
• PKA: 3.53±0.40(Predicted)
• CAS DataBase Reference: (R)-3-((BENZYLOXY)CARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-((BENZYLOXY)CARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID(161891-81-2)
• EPA Substance Registry System: (R)-3-((BENZYLOXY)CARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID(161891-81-2)

Safety Data

• Hazardous Substances Data: 161891-81-2(Hazardous Substances Data)

Usage

General Description

(R)-3-((Benzyloxy)carbonyl)-2,2-dimethyloxazolidine-4-carboxylic acid is a synthetic chemical compound with potential pharmaceutical applications. It is a derivative of oxazolidinone, a class of antibiotics used to treat various bacterial infections. (R)-3-((BENZYLOXY)CARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID contains a carboxylic acid group, a benzyl ester group, and a dimethyl oxazolidine ring. The presence of these functional groups makes it a versatile building block for the synthesis of other bioactive molecules. (R)-3-((BENZYLOXY)CARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID has the potential to exhibit antimicrobial activity and may have use in the development of new antibiotics. It is also a chiral molecule, with a specific configuration around the oxazolidine ring, which may be important for its biological activity. Overall, (R)-3-((Benzyloxy)carbonyl)-2,2-dimethyloxazolidine-4-carboxylic acid is a promising compound for further research and development in the pharmaceutical industry.

Upstream product

• 1145-80-8 N-(benzyloxycarbonyl)-L-serine 
• 77-76-9 2,2-dimethoxy-propane 
• 501-53-1 benzyl chloroformate 
• 1676-81-9 N-benzyloxycarbonyl-L-serine methyl ester 

Downstream Products

• 1569294-33-2 C₂₅H₂₉ClN₂O₅ 
• 1168208-15-8 (S)-4-((E)-(R)-3-ethoxycarbonyl-1-hydroxymethyl-2-methyl-allylcarbamoyl)-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester 
• 334832-25-6 (S)-2-{[2-((S)-1-Benzyloxycarbonylamino-2-triethylsilanyloxy-ethyl)-5-methyl-oxazole-4-carbonyl]-amino}-3-(tert-butyl-diphenyl-silanyloxy)-propionic acid methyl ester 
• 334832-23-4 (S)-4-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methoxycarbonyl-ethylcarbamoyl]-5,2',2'-trimethyl-4',5'-dihydro-[2,4']bioxazolyl-3'-carboxylic acid benzyl ester 
• 334832-24-5 (S)-2-{[2-((S)-1-Benzyloxycarbonylamino-2-hydroxy-ethyl)-5-methyl-oxazole-4-carbonyl]-amino}-3-(tert-butyl-diphenyl-silanyloxy)-propionic acid methyl ester 
• 334832-20-1 (S)-4-((1S,2R)-2-Hydroxy-1-methoxycarbonyl-propylcarbamoyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 334832-22-3 (S)-5,2',2'-Trimethyl-4',5'-dihydro-[2,4']bioxazolyl-4,3'-dicarboxylic acid 3'-benzyl ester 
• 334832-21-2 (S)-5,2',2'-Trimethyl-4',5'-dihydro-[2,4']bioxazolyl-4,3'-dicarboxylic acid 3'-benzyl ester 4-methyl ester 
• 666215-53-8 4-{2-(tert-butyl-dimethyl-silanyloxy)-1-[6-dimethoxymethyl-3-(4-ethoxycarbonyl-thiazol-2-yl)-pyridin-2-yl]-ethylcarbamoyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 500354-62-1 2-[(S)-1-{(S)-2-[((S)-3-Benzyloxycarbonyl-2,2-dimethyl-oxazolidine-4-carbonyl)-amino]-3-hydroxy-3-methyl-butyrylamino}-2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-5-methyl-oxazole-4-carboxylic acid methyl ester 
• 160821-20-5 (4S)-N-benzyloxycarbonyl-4-carbamoyl-2,2-dimethyl-1,3-oxazolidine 

Relevant articles and documents

Enantioselective organocatalytic conjugate reduction of β-AzoleContaining α,β-unsaturated aldehydes

β-Azole-contalnlng α,β-unsaturated aldehydes were successfully reduced under highly enantloselectlve organocatalytlc transfer hydrogenation conditions. The products were obtained In good yields and up to 94% optical purity. This simple process was success

Useful synthesis of the main dehydrohexapeptide segment of a macrocyclic antibiotic, berninamycin B

The useful synthesis of tetradehydrohexapeptide segment 2, which is the main skeleton of a macrocyclic antibiotic, berninamycin B, was first achieved. The skeleton 2 is constructed, in turn, of 2-[(Z)-1-amino-1-propenyl]-5-methyl-oxazole-4-carboxylic acid, α-dehydroalanine (ΔAla), L-Val, 2-[1-amino-1-ethenyl]-5-methyloxazole-4-carboxylic acid residues, besides L-Thr and ΔAla at the N- and C-termini, respectively.