161925-36-6Relevant academic research and scientific papers
Titanium(IV)-mediated tandem deprotection-cyclodehydration of protected cysteine N-amides: Biomimetic syntheses of thiazoline- and thiazole-containing heterocycles
Raman, Prakash,Razavi, Hossein,Kelly, Jeffery W.
, p. 3289 - 3292 (2007/10/03)
(matrix presented) The scope and limitations of TiCl4-mediated Δ2-thiazoline synthesis via tandem deprotection-dehydrocyclization of trityl-protected cysteine N-amides is presented. While chemical yields are acceptable (53-96%), the
Polymer-bound triarylphosphine-iodine complexes, convenient coupling reagent systems in peptide synthesis
Caputo,Cassano,Longobardo,Mastroianni,Palumbo
, p. 141 - 143 (2007/10/02)
N-protected α-amino acids are readily coupled with α-aminoacyl esters by polystyryl diphenylphosphine-iodine complex in very high yields and without detectable racemization. Protecting groups of general use for both amine and carboxyl functions, as well a
