Welcome to LookChem.com Sign In|Join Free


  • or


Post Buying Request

103213-32-7 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • Fmoc-Cys(Trt)-OH Non-animal Origin, FMOC-L-CYSTEINE(TRT)-OH, High Purity & High Chirality SPPS Building Block; MFCD00038538

    Cas No: 103213-32-7

  • USD $ 60.0-76.0 / Gram

  • 1 Gram

  • 500 Kilogram/Month

  • GL Biochem (Shanghai) Ltd.
  • Contact Supplier

103213-32-7 Usage

Chemical Properties

white to light yellow crystal powde


Different sources of media describe the Uses of 103213-32-7 differently. You can refer to the following data:
1. It is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.
2. Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.

General Description

The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP?, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.The product number for this product was previously 04-12-1018.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Check Digit Verification of cas no

The CAS Registry Mumber 103213-32-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,2,1 and 3 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 103213-32:
57 % 10 = 7
So 103213-32-7 is a valid CAS Registry Number.

103213-32-7 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • TCI America

  • (F0652)  N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine  >98.0%(HPLC)(T)

  • 103213-32-7

  • 5g

  • 490.00CNY

  • Detail
  • TCI America

  • (F0652)  N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine  >98.0%(HPLC)(T)

  • 103213-32-7

  • 25g

  • 1,350.00CNY

  • Detail
  • Alfa Aesar

  • (H27363)  N-Fmoc-S-trityl-L-cysteine, 95%   

  • 103213-32-7

  • 1g

  • 182.0CNY

  • Detail
  • Alfa Aesar

  • (H27363)  N-Fmoc-S-trityl-L-cysteine, 95%   

  • 103213-32-7

  • 5g

  • 419.0CNY

  • Detail
  • Alfa Aesar

  • (H27363)  N-Fmoc-S-trityl-L-cysteine, 95%   

  • 103213-32-7

  • 25g

  • 973.0CNY

  • Detail
  • Aldrich

  • (47695)  Fmoc-Cys(Trt)-OH  ≥95.0% (sum of enantiomers, HPLC)

  • 103213-32-7

  • 47695-5G

  • 402.48CNY

  • Detail
  • Aldrich

  • (47695)  Fmoc-Cys(Trt)-OH  ≥95.0% (sum of enantiomers, HPLC)

  • 103213-32-7

  • 47695-25G

  • 875.16CNY

  • Detail
  • Aldrich

  • (47695)  Fmoc-Cys(Trt)-OH  ≥95.0% (sum of enantiomers, HPLC)

  • 103213-32-7

  • 47695-100G

  • 2,625.48CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017


1.1 GHS Product identifier

Product name FMOC-S-trityl-L-cysteine

1.2 Other means of identification

Product number -
Other names N-Fmoc-S-trityl-L-cysteine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103213-32-7 SDS

103213-32-7Relevant articles and documents

Investigation of Cysteine as an Activator of Side-Chain N→S Acyl Transfer and Tail-to-Side-Chain Cyclization

Castillo-Pazos, Durbis J.,Macmillan, Derek

, p. 1923 - 1928 (2017)

N→S Acyl transfer is a popular method for the postsynthesis production of peptide C α -thioesters for use in native chemical ligation and for the synthesis of head-to-tail cyclic peptides. Meanwhile thioester formation at the side chain of aspartic or glutamic acids, leading to tail-to-side-chain-cyclized species, is less common. Herein we explore the potential for cysteine to function as a latent thioester when appended to the side chain of glutamic acid. Initial insights gained through study of C-terminal β-alanine as a model for the increased chain length were ultimately applied to peptide macrocyclization. Our results emphasize the increased barrier to acyl transfer at the glutamic acid side chain and indicate how a slow reaction, facilitated by cysteine itself, may be accelerated by fine-tuning of the stereoelectronic environment..

A comprehensive one-pot synthesis of protected cysteine and selenocysteine SPPS derivatives

Flemer, Stevenson

, p. 1257 - 1264 (2015/04/14)

A proof-of-principle methodology is presented in which all commercially-available cysteine (Cys) and selenocysteine (Sec) solid phase peptide synthesis (SPPS) derivatives are synthesized in high yield from easily prepared protected dichalcogenide precursors. A Zn-mediated biphasic reduction process applied to a series of four bis-Nα-protected dichalcogenide compounds allows facile conversion to their corresponding thiol and selenol intermediates followed by insitu S- or Se-alkylation with various electrophiles to directly access twenty one known Cys and Sec SPPS derivatives. Most of these derivatives were able to be precipitated in crude form out of petroleum ether in sufficient purity for direct use as peptide building blocks. Subsequent incorporation of these derivatives into peptide models nicely illustrates their viability and applicability toward SPPS.

Treating disorders by application of insulin-like growth factors and analogs


, (2008/06/13)

A method of enhancing the survival of neuronal cells in a mammal, the cells being at risk of dying, the method including the step of administering to the mammal one of the following substances: IGF-I; a functional derivative of IGF-I; IGF-II; a functional derivative of IGF-II; IGF-III; or a functional derivative of IGF-III.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)


What can I do for you?
Get Best Price

Get Best Price for 103213-32-7