161987-01-5Relevant academic research and scientific papers
Benzo-1,6-naphthyridine Synthesis via Intramolecular Diels-Alder Reactions of Aryl Oxazoles: Synthetic Approach to 2-Bromoleptoclinidinone
Jung, Michael E.,Dansereau, Susan M.K.
, p. 767 - 778 (2007/10/02)
A new route for the synthesis of benzo-1,6-naphthyridines is described.The method involves the intramolecular Diels-Alder cycloaddition of aryl oxazoles with substituted acrylamides to give pyridines and was developed as a route to the antileukemic aromatic alkaloid 2-bromoleptoclinidinone.
