62882-10-4Relevant academic research and scientific papers
BENZOCARBONYL COMPOUNDS
-
Paragraph 00500, (2019/06/23)
Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.
Imidazoline derivatives as alpha-1A adrenoceptor ligands
-
Page/Page column 36, (2010/02/11)
Compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Such compounds are useful in the treatment of Alpha-1A mediated diseases or conditions such as urinary incontinence.
POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR
-
Page 69, (2010/02/08)
The invention provides compounds of Formula (I). These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in wh
2-(anilinomethyl)imidazolines as alpha1A adrenergic receptor agonists: 2'-heteroaryl and 2'-oxime ether series.
Navas 3rd., Frank,Bishop, Michael J,Garrison, Deanna T,Hodson, Stephen J,Speake, Jason D,Bigham, Eric C,Drewry, David H,Saussy, David L,Liacos, James H,Irving, Paul E,Gobel, M Jeffrey
, p. 575 - 579 (2007/10/03)
A series of 2'-heteroaryl and 2'-oxime anilinomethylimidazolines was prepared and evaluated in in vitro functional assays for cloned human alpha1A, alpha1B, and alpha1D receptor subtypes. Potent and selective alpha1A agonists have been identified in these series.
Benzamide derivatives having a vasopressin antagonistic activity
-
, (2008/06/13)
This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc. and represented by general formula (I): wherein R1is aryl optionally substituted with lower alkoxy, etc., R2is lower alkyl, etc., R3is hydrogen, etc., A is NH, etc., E is etc., X is —CH═CH—, —CH═N—, or S, and Y is a condensed heterocyclic group, etc., and pharmaceutically acceptable salts thereof, to processes for preparation thereof and to a pharmaceutical composition comprising the same.
Herbicidal sulfonamides
-
, (2008/06/13)
This invention relates to ortho-heterocyclic benzene sulfonylureas which are useful as herbicides and growth regulants.
