1619970-78-3

Basic information

• Product Name: (E)-ethyl 2-(4-methoxybenzylidene)-4-oxo-4-phenylbutanoate
• Synonyms: (E)-ethyl 2-(4-methoxybenzylidene)-4-oxo-4-phenylbutanoate
• CAS NO: 1619970-78-3
• Molecular Weight: 324.376
• Mol File: 1619970-78-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-ethyl 2-(4-methoxybenzylidene)-4-oxo-4-phenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-ethyl 2-(4-methoxybenzylidene)-4-oxo-4-phenylbutanoate(1619970-78-3)
• EPA Substance Registry System: (E)-ethyl 2-(4-methoxybenzylidene)-4-oxo-4-phenylbutanoate(1619970-78-3)

Safety Data

• Hazardous Substances Data: 1619970-78-3(Hazardous Substances Data)

Upstream product

• 15121-89-8 ethyl (E)-4-oxo-4-phenyl-2-butenoate 
• 123-11-5 4-methoxy-benzaldehyde 
• 2206-94-2 1-acetoxy-1-phenylethene 
• 66051-40-9 (E)-methoxyphenyl-3 chloro-2 propenoate d'ethyle 
• 6742-53-6 (E)-ethyl 4-oxo-2-pentenoate 

Downstream Products

• 57999-76-5 4-(4-methoxybenzyl)-6-phenylpyridazin-3(2H)-one 

Relevant articles and documents

Ir(ppy)3-Catalyzed, Visible-Light-Mediated Reaction of α-Chloro Cinnamates with Enol Acetates: An Apparent Halogen Paradox

The visible-light-mediated activation of vinyl chlorides derived from α-chloro ethyl cinnamates via oxidative quenching of excited photocatalyst fac-Ir(ppy)3 is described. Upon photoelectron transfer and chloride extrusion, the corresponding vinyl radical can be efficiently trapped by enol acetates, giving rise to synthetically useful 1,4-dicarbonyl compounds in good to excellent yields. This transformation is distinguished by mild and environmentally benign reaction conditions and can be performed on a multigram scale, in sharp contrast to contrasting α-bromo ethyl cinnamates, which show low conversion under the various conditions applied.

Synthesis of multi-functional alkenes via Wittig reaction with a new-type of phosphorus ylides

A Bu3P-mediated mild and efficient synthesis of multi-functional alkenes has been described starting from substituted acrylate with aldehydes. In situ generated zwitterionic intermediates underwent proton-exchange to afford ylide intermediates, which were trapped by corresponding aldehydes providing the products in up to 92% yield with complete E-stereoselectivity. Further derivatization of the products was performed to furnish functional pyridazinones.