1620058-92-5

Basic information

• Product Name: ethyl 3-azido-2-hydroxy-2-methyl-4-oxo-4-(p-tolyl)butanoate
• Synonyms: ethyl 3-azido-2-hydroxy-2-methyl-4-oxo-4-(p-tolyl)butanoate
• CAS NO: 1620058-92-5
• Molecular Weight: 291.307
• Mol File: 1620058-92-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 3-azido-2-hydroxy-2-methyl-4-oxo-4-(p-tolyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-azido-2-hydroxy-2-methyl-4-oxo-4-(p-tolyl)butanoate(1620058-92-5)
• EPA Substance Registry System: ethyl 3-azido-2-hydroxy-2-methyl-4-oxo-4-(p-tolyl)butanoate(1620058-92-5)

Safety Data

• Hazardous Substances Data: 1620058-92-5(Hazardous Substances Data)

Upstream product

• 617-35-6 2-oxo-propionic acid ethyl ester 
• 6595-30-8 2-azido-1-(4-methylphenyl)ethan-1-one 

Relevant articles and documents

Asymmetric aldol addition of α-azido ketones to ethyl pyruvate mediated by a cinchona-based bifunctional urea catalyst Dedicated to the memory of Prof. Dr. Ayhan S. Demir

The first asymmetric synthesis of ethyl 4-aryl-3-azido-2-hydroxy-2-methyl- 4-oxobutanoates via a cinchona organocatalyst induced aldol addition of α-azido ketones to ethyl pyruvate has been developed. The coupling reaction under optimized conditions was carried out to furnish tetrafunctionalized synthons with enantioselectivities of up to 91:9 and enriched diastereoselectivities of up to 95:5 (syn:anti).