162011-50-9Relevant academic research and scientific papers
Alkylbenzyl ethers of hydroquinones as monoamine oxidase B inhibitors
Arvanitis, Argyrios G.,Scholfield, Everett L.,Grigoriadis, Dimitri,Heytler, Peter G.,Bowdle, Jack,Chorvat, Robert J.
, p. 115 - 120 (1996)
A series of alkylbenzylethers of substituted hydroquinone analogs of 4-(3-chlorophenyl methyloxy)-phenoxybutyronitrile I, and alcohol II were synthesized as monoamine oxidase (MAO) inhibitors. Incorporation of electron-withdrawing groups on the hydroquinone afforded compounds with higher levels of activity and selectivity than I or II for MAO B inhibition.
ALKYL AND ALKYLBENZYL ETHERS OF SUBSTITUTED HYDROQUINONES
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, (2008/06/13)
The present invention provides alkyl and alkylbenzyl ethers of substituted hydroquinones and pharmaceutical compositions containing them. The present invention further provides methods of using these compounds and compositions to inhibit monoamine oxidase, particularly monoamine oxidase B. The present invention further provides methods for the treatment of diseases involving monoamine oxidase
