1620124-65-3

Upstream product

• 949158-26-3 N₃-benzoyl-2'-O-(2-methoxycarbonylethyl)-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 86988-35-4 3-benzoyl-1-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]pyrimidine-2,4(1H,3H)-dione 

Downstream Products

• 1620124-68-6 N³-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxycarbonylethyl)uridine 
• 1620124-70-0 5′-O-(4,4′-dimethoxytrityl)-N³-benzoyl-2′-O-(2-methoxycarbonylethyl)uridine 3′-(2-cyanoethyl N,N-diisopropylphosphoramidite) 

Relevant academic research and scientific papers

Synthesis and properties of oligonucleotides modified with 2′-O-(2-carboxyethyl)nucleotides and their carbamoyl derivatives

2′-O-Methyl oligoribonucleotides with four kinds of 2′-O-modified uridine derivatives were synthesised. Their duplex stability, hydration behavior and exonuclease resistance were studied by spectroscopic analyses and molecular dynamics simulations. Conseq