86988-35-4Relevant articles and documents
Synthesis and in vitro growth inhibitory activity of novel silyl- and trityl-modified nucleosides
Panayides, Jenny-Lee,Mathieu, Véronique,Banuls, Laetitia Moreno Y.,Apostolellis, Helen,Dahan-Farkas, Nurit,Davids, Hajierah,Harmse, Leonie,Rey, M.E. Christine,Green, Ivan R.,Pelly, Stephen C.,Kiss, Robert,Kornienko, Alexander,Van Otterlo, Willem A.L.
, p. 2716 - 2724 (2016/06/08)
Seventeen silyl- and trityl-modified (5′-O- and 3′,5′-di-O-) nucleosides were synthesized with the aim of investigating the in vitro antiproliferative activities of these nucleoside derivatives. A subset of the compounds was evaluated at a fixed concentra
An improved transient method for the synthesis of N-benzoylated nucleosides
Zhu, Xue-Feng,Williams Jr., Howard J.,Scott, A. Ian
, p. 1233 - 1243 (2007/10/03)
The Jones' transient method for the synthesis of N-benzoylated nucleosides is improved by reducing the amounts of chlorotrimethylsilane (TMSCl) and benzoyl chloride to nearly equivalent quantities. The easy work-up and high yields of products are the major advantages of this approach. Jones' method is further simplified by omitting the addition of ammonium hydroxide. The utility of this modification for the preparation of some useful protected nucleosides is also presented.
Synthesis of Modified Oligodeoxyribonucleotides Containing 1-(2-Amino-2-deoxy-β-D-arabinofuranosyl)uracil
Kachalova,Zubin
, p. 236 - 238 (2007/10/03)
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