1620136-60-8

Basic information

• Product Name: (S)-5-bromo-2-(2-(trifluoromethyl)pyrrolidin-1-yl)pyrimidine
• Synonyms: (S)-5-bromo-2-(2-(trifluoromethyl)pyrrolidin-1-yl)pyrimidine
• CAS NO: 1620136-60-8
• Molecular Formula: C9H9BrF3N3
• Molecular Weight: 296.0870696
• Mol File: 1620136-60-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 334.5±50.0 °C(Predicted)
• Appearance: /
• Density: 1.648±0.06 g/cm3(Predicted)
• PKA: 2.44±0.42(Predicted)
• CAS DataBase Reference: (S)-5-bromo-2-(2-(trifluoromethyl)pyrrolidin-1-yl)pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-bromo-2-(2-(trifluoromethyl)pyrrolidin-1-yl)pyrimidine(1620136-60-8)
• EPA Substance Registry System: (S)-5-bromo-2-(2-(trifluoromethyl)pyrrolidin-1-yl)pyrimidine(1620136-60-8)

Safety Data

• Hazardous Substances Data: 1620136-60-8(Hazardous Substances Data)

Upstream product

• 1389310-06-8 (S)-2-(trifluoromethyl)pyrrolidine hydrochloride 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 119580-41-5 (S)-(+)-2-(trifluoromethyl)pyrrolidine 

Downstream Products

• 1620136-62-0 (S)-6-(2-(2-(trifluoromethyl)pyrrolidin-1-yl)pyrimidin-5-yl)pyridine-2-amine 
• 1620136-70-0 (S)-6-(2-(2-(trifluoromethyl)pyrrolidin-1-yl)pyrimidin-5-yl)pyrazin-2-amine 
• 1620136-61-9 (S)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2-(trifluoromethyl)pyrrolidin-1-yl)pyrimidine 

Relevant articles and documents

INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL

The present invention relates to pharmaceutical compounds of the Formula (I), or a pharmaceutically acceptable salt or composition thereof, and methods of their use for the treatment of pain, respiratory conditions, as well as inhibiting the Transient Receptor Potential Al ion channel (TRPA1).

INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL

This disclosure describes novel compounds and pharmaceutical compositions for inhibiting the TRPA1 ion channel and/or medical conditions related to TRPA1, such as pain and respiratory conditions.