1620144-02-6Relevant academic research and scientific papers
Selective Kumada biaryl cross-coupling reaction enabled by an iron(iii) alkoxide-N-heterocyclic carbene catalyst system
Chua, Yi-Yuan,Duong, Hung A.
, p. 8424 - 8427 (2014)
A catalyst system comprising Fe2(OtBu)6 and an N-heterocyclic carbene ligand enables efficient syntheses of (hetero)biaryls from the reactions of aryl Grignard reagents with a diverse spectrum of (hetero)aryl chlorides. Amongst the alkoxide and amide counterions investigated, tert-butoxide was the most effective in inhibiting the homocoupling of arylmagnesiums. This journal is the Partner Organisations 2014.
Iron(ii) triflate/N-heterocyclic carbene-catalysed cross-coupling of arylmagnesiums with aryl chlorides and tosylates
Chua, Yi-Yuan,Duong, Hung A.
supporting information, p. 1466 - 1469 (2016/01/25)
In comparison to iron(ii) halides, iron(ii) triflate exhibits a greater resistance towards reduction by p-tolylmagnesium bromide. This knowledge has led to the development of an iron(ii) triflate/N-heterocyclic carbene-catalysed cross-coupling system of aryl Grignard reagents with aryl chlorides and tosylates with high efficiency, even surpassing that of previously reported catalyst systems employing strongly coordinating counterions in some cases.
