1620195-79-0Relevant academic research and scientific papers
Nucleophilic fluorination of α-aroylphosphinates with morpholinosulfur trifluoride
Zasukha, Sergiy V.,Guzyr, Olexandr I.,Shermolovich, Yuriy G.
, p. 256 - 264 (2014)
Nucleophilic fluorination of aroyl-phenyl-phosphinates is highly dependent on the nature of the alkoxy substituents attached to the phosphoryl group. A reaction of aroyl-phenyl-phosphinates with morpholinosulfur trifluoride was shown to be a convenient synthetic method for high-yield synthesis of α,α-difluorobenzyl-phenyl-phosphinates using steric protection of the phosphoryl group by a bulky isopropoxy substituent. The methyl esters of aroylphosphinic acids in the same reaction conditions yield (fluoro-diaryl- methyl)-pentafluorophosphates as the main reaction products.
