22950-57-8

Basic information

• Product Name: Phosphonic acid, benzoyl-, bis(1-methylethyl) ester
• CAS NO: 22950-57-8
• Molecular Formula: C13H19O4P
• Molecular Weight: 270.265
• Mol File: 22950-57-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, benzoyl-, bis(1-methylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, benzoyl-, bis(1-methylethyl) ester(22950-57-8)
• EPA Substance Registry System: Phosphonic acid, benzoyl-, bis(1-methylethyl) ester(22950-57-8)

Safety Data

• Hazardous Substances Data: 22950-57-8(Hazardous Substances Data)

Upstream product

• 513-02-0 triisopropyl phosphate 
• 98-88-4 benzoyl chloride 
• 591-50-4 iodobenzene 
• 1809-20-7 diisopropyl hydrogenphosphonate 
• 201230-82-2 carbon monoxide 
• 33876-85-6 benzoylphosphonic acid di(trimethylsilyl) ester 
• 18106-71-3 dimethyl benzoylphosphonate 
• 6881-61-4 benzoylphosphonic acid 
• 67-63-0 isopropyl alcohol 
• 27344-79-2 sodium diisopropyl phosphite 
• 116-17-6 triisopropyl phosphite 

Downstream Products

• 1809-20-7 diisopropyl hydrogenphosphonate 
• 1485-70-7 N-benzylbenzamide 
• 74449-29-9 [(Diisopropoxy-phosphoryloxy)-phenyl-methyl]-phosphonic acid diisopropyl ester 
• 145298-97-1 2-propyl hydrogen benzoylphosphonate 
• 145298-96-0 P,P'-dibenzoylpyrophosphonic dichloride 
• 1602490-02-7 diisopropyl (S)-hydroxy[(2R)-5-oxo-2,5-dihydrofuran-2-yl]phenylmethylphosphonate 
• 154109-20-3 (Hydroxyamino-phenyl-methyl)-phosphonic acid diisopropyl ester 
• 114987-81-4 (RS)-<(hydroxyamino)(phenyl)methyl>phosphonic acid 

Relevant articles and documents

Carbene-catalyzed enal γ-carbon addition to α-ketophosphonates for enantioselective access to bioactive 2-pyranylphosphonates

A carbene-catalyzed enantioselective [4+2] cycloaddition reaction between α,β-unsaturated aldehydes and α-ketophosphonates is developed. The reaction affords chiral 2-pyranylphosphonates with excellent enantioselectivities. The optically enriched phosphonate products bear multiple functional groups, including unsaturated lactone and phosphonate moieties that often lead to unique bio-activities. Preliminary studies show that the products from our reactions exhibit anti-bacterial (X. oryzae pv. oryzae) and anti-viral (Tobacco Mosaic Virus) activities for potential use in plant protection.

Rhodium-catalyzed enantioselective cyclizations of γ-alkynylaldehydes with acyl phosphonates: ligand- and substituent-controlled C-P or C-H bond cleavage

It has been established that a cationic rhodium(I)/(R)-H8-BINAP or (R)-Segphos complex catalyzes two modes of enantioselective cyclizations of γ-alkynylaldehydes with acyl phosphonates via C-P or C-H bond cleavage. The ligands of the Rh(I) comp

Reactions of acyl tributylphosphonium chlorides and dialkyl acylphosphonates with Grignard and organolithium reagents

Ketones and esters (4) were effectively prepared by reaction of Grignard reagents with acyl tributylphosphonium chlorides (2), diethyl acylphosphonates (5), or diisopropyl acylphosphonate (6) derived from acid chlorides and chloroformates (1). Although by the method with 2, 4 is prepared in one-pot operation from 1 and generally in a higher yield, the method with 5 or 6 proved to compensate for the synthesis of 4 with 2 in some respects. The reactivities of 2, 5, and 6 as electrophiles were also evaluated by comparing their reduction potential with those of acid chlorides.