1620562-54-0

Basic information

• Product Name: N-(1H-indol-6-yl)acrylamide
• Synonyms: N-(1H-indol-6-yl)acrylamide
• CAS NO: 1620562-54-0
• Molecular Weight: 186.213
• Mol File: 1620562-54-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(1H-indol-6-yl)acrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1H-indol-6-yl)acrylamide(1620562-54-0)
• EPA Substance Registry System: N-(1H-indol-6-yl)acrylamide(1620562-54-0)

Safety Data

• Hazardous Substances Data: 1620562-54-0(Hazardous Substances Data)

Upstream product

• 5318-27-4 6-amino-1H-indole 
• 814-68-6 acryloyl chloride 

Relevant articles and documents

Novel 5-arylcarbamoyl-2-methylisoxazolidin-3-yl-3-phosphonates as nucleotide analogues

A series of 5-substituted 3-phosphonylated isoxazolidines have been obtained via cycloaddition of N-methyl-C-(diethoxyphosphoryl)nitrone with N-heteroaromatic acrylamides. Good trans/cis diastereoselectivities (d.e. 58-76%) of isomeric (3-diethoxyphosphoryl)isoxazolidines were observed. cis-and trans-Isoxazolidine phosphonates were evaluated for their antiviral activity against a broad range of DNA and RNA viruses but were found inactive. Their cytostatic activity toward L1210, CEM, and HeLa cells was also established, and compounds cis-12r and trans-11r having a 2,2-difluorobenzo[d][1,3]dioxole moiety slightly inhibited proliferation of HeLa cells at IC50 values of 186 and 179 M, respectively.