1620646-06-1

Basic information

• Product Name: N-but-3-enyl-3,4-dimethoxy-N-phenyl-benzamide
• Synonyms: N-but-3-enyl-3,4-dimethoxy-N-phenyl-benzamide
• CAS NO: 1620646-06-1
• Molecular Weight: 311.381
• Mol File: 1620646-06-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-but-3-enyl-3,4-dimethoxy-N-phenyl-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-but-3-enyl-3,4-dimethoxy-N-phenyl-benzamide(1620646-06-1)
• EPA Substance Registry System: N-but-3-enyl-3,4-dimethoxy-N-phenyl-benzamide(1620646-06-1)

Safety Data

• Hazardous Substances Data: 1620646-06-1(Hazardous Substances Data)

Upstream product

• 778-29-0 but-3-enyl 4-methylbenzenesulfonate 
• 1522-67-4 N-phenyl-3,4-dimethoxybenzamide 

Downstream Products

• 1620646-07-2 3,4-dimethoxy-N-[(E)-5-oxopent-3-enyl]-N-phenyl-benzamide 
• 1620644-83-8 N-[2-(3-acetyl-1-benzyl-4H-pyridin-4-yl)ethyl]-3,4-dimethoxy-N-phenyl-benzamide 
• 1620644-87-2 N-[2-(3-acetyl-1-benzyl-pyridin-1-ium-4-yl)ethyl]-3,4-dimethoxy-N-phenyl-benzamide 2,3-dichloro-5,6-dicyano-4-oxo-cyclohex-1,5-dien-1-olate 

Relevant articles and documents

OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS

A compound of formula (I) in which the dotted lines indicate the presence of at least one double bond; n = 0 to 4; R3 and R4 are H, or when n = 1, R3 and R4 can also form together a double bond between the carbon atoms, and m = 0, 1 or 2, Z is CH or N or Z is C and - CHR3- is =CH- linked by the double bond to cyclopentanone; or - (-)m- is absent, and Z is NH, >N-alkyl, >N-phenyl, >N-benzyl or >N heteroaryl; R8 is alkyl, aryl or heteroaryl which can be optionally substituted; EWG represents an electron withdrawing group selected from the group comprising COOR, COSR, CONRR', CN, COR, CF3, SOR, SO2R, SONRR', SO2NRR', NO2, halogen, heteroaryl; and the pharmaceutical salts and stereisomers thereof. The compounds of formula (I) are potent in the treatment of neurodegenerative diseases such as Alzheimer's disease.