1620650-75-0Relevant academic research and scientific papers
Catalytic enantioselective inverse electron demand hetero-diels-alder reaction with allylsilanes
Matsumura, Yuki,Suzuki, Takahiro,Sakakura, Akira,Ishihara, Kazuaki
, p. 6131 - 6134 (2014/06/23)
The first diastereo- and enantioselective inverse electron demand hetero-Diels-Alder reaction of β,γ-unsaturated α-ketoesters with allylsilanes is described. Chiral copper(II) catalysts successfully activate the β,γ-unsaturated α-ketoesters and promote the reaction with allylsilanes with excellent enantioselectivities. This process represents a new entry to chiral oxanes.
