1620742-32-6

Basic information

• Product Name: C₁₆H₁₄BrN
• Synonyms: C₁₆H₁₄BrN
• CAS NO: 1620742-32-6
• Molecular Weight: 300.198
• Mol File: 1620742-32-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₄BrN(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₄BrN(1620742-32-6)
• EPA Substance Registry System: C₁₆H₁₄BrN(1620742-32-6)

Safety Data

• Hazardous Substances Data: 1620742-32-6(Hazardous Substances Data)

Upstream product

• 766-96-1 4-bromo-1-ethynylbenzene 
• 698-02-2 N,N-dimethyl-o-iodoaniline 

Downstream Products

• 1094473-56-9 (4-bromophenyl)(1-methyl-1H-indol-3-yl)methanone 

Relevant articles and documents

Synthesis of: N -alkyl-3-sulfonylindoles and N -alkyl-3-sulfanylindoles by cascade annulation of 2-alkynyl- N, N -dialkylanilines

An efficient and metal-free approach to N-alkyl-3-sulfonylindoles and N-alkyl-3-sulfanylindoles from 2-alkynyl-N,N-dialkylanilines has been developed. In the presence of iodine and tert-butylhydroperoxide (TBHP), a variety of 2-alkynyl-N,N-dialkylanilines underwent a cascade radical annulation to yield 3-arylsulfonylindoles. In contrast, 3-arylsulfanylindoles were conveniently prepared by iodine mediated electrophilic annulation reactions. The present protocol uses the economical and environmentally friendly I2-TBHP or I2 system, and potentially bioactive N-alkyl-3-sulfonylindoles and N-alkyl-3-sulfanylindoles with various functional groups were successfully synthesized in moderate to good yields.