1620809-37-1Relevant academic research and scientific papers
Regioselective conversion of arenes to N-aryl-1,2,3-triazoles Using C-H Borylation
Srinivasan, Rajavel,Coyne, Anthony G.,Abell, Chris
, p. 11680 - 11684 (2014)
A one-pot protocol for the synthesis of N-aryl 1,2,3-triazoles from arenes by an iridium-catalyzed C-H borylation/copper catalyzed azidation/click sequence is described. 1mol % of Cu(OTf)2 was found to efficiently catalyze both the azidation and the click reaction. The applicability of this method is demonstrated by the late-stage chemoselective installation of 1,2,3-triazole moiety into unactivated molecules of pharmaceutical importance.
Synthesis of diverse 3-azido-5-(azidomethyl)benzene derivatives via formal C-H azidation and functional group-selective transformations
Nishiyama, Yoshitake,Misawa, Yoshihiro,Hazama, Yuki,Oya, Kazuhiro,Yoshida, Suguru,Hosoya, Takamitsu
, p. 1053 - 1072 (2019/07/31)
3-Azido-5-(azidomethyl)benzene derivatives are useful compounds for preparing diverse bistriazole compounds and photoaffinity probes for target identification of bioactive compounds. To more easily synthesize a diverse range of diazido compounds, a facile
Formal C-H-azidation-based shortcut to diazido building blocks for the versatile preparation of photoaffinity labeling probes
Yoshida, Suguru,Misawa, Yoshihiro,Hosoya, Takamitsu
supporting information, p. 3991 - 3995 (2014/07/08)
Short synthetic routes to diazido building blocks with different connectable groups were established on the basis of the sequential iridium-catalyzed C-H borylation and copper-catalyzed azidation of 1,3-disubstituted benzenes, followed by diverse azido-fr
