1620841-75-9Relevant articles and documents
Synthesis and antiproliferative activity of novobiocin analogues as potential hsp90 inhibitors Dedicated to the memory of Dr. Christine Radanyi.
Audisio, Davide,Methy-Gonnot, Délphine,Radanyi, Christine,Renoir, Jack-Michel,Denis, Stéphanie,Sauvage, Félix,Vergnaud-Gauduchon, Juliette,Brion, Jean-Daniel,Messaoudi, Samir,Alami, Mouad
, p. 498 - 507 (2014/07/21)
A series of substituted coumarins1-10 was designed and synthesized as a novel class of 4TCNA analogues. Compound 2a showed excellent antiproliferative activity with mean GI50 values at a micromolar level in a diverse set of human cancer cells (