16209-00-0

Basic information

• Product Name: 4-(1H-PYRAZOL-1-YL)BENZOIC ACID
• Synonyms: benzoic acid, 4-(1H-pyrazol-1-yl)-;4-(1H-pyrazol-1-yl)benzoic acid(SALTDATA: FREE);4-(1-Pyrazolyl)benzoic Acid;Benzoic acid, 4-(pyrazol-1-yl)-;AKOS BBS-00002744;4-PYRAZOL-1-YL-BENZOIC ACID;4-(1H-PYRAZOL-1-YL)BENZOIC ACID;CHEMBRDG-BB 4400951
• CAS NO: 16209-00-0
• Molecular Formula: C₁₀H₈N₂O₂
• Molecular Weight: 188.18
• Product Categories: Carboxylic Acids;Phenyls & Phenyl-Het;Heterocyclic Compounds;Carboxylic Acids;Phenyls & Phenyl-Het;Building Blocks;Heterocyclic Building Blocks;Pyrazoles;Acids and Derivatives;Heterocycles
• Mol File: 16209-00-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 269 °C
• Boiling Point: 360.4±25.0 °C at 760 mmHg
• Flash Point: 171.8±23.2 °C
• Appearance: /
• Density: 1.3±0.1 g/cm³
• Vapor Pressure: 8E-06mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.01±0.10(Predicted)
• CAS DataBase Reference: 4-(1H-PYRAZOL-1-YL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1H-PYRAZOL-1-YL)BENZOIC ACID(16209-00-0)
• EPA Substance Registry System: 4-(1H-PYRAZOL-1-YL)BENZOIC ACID(16209-00-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 16209-00-0(Hazardous Substances Data)

Usage

General Description

4-(1H-Pyrazol-1-yl)benzoic acid is a chemical compound with the molecular formula C11H8N2O2. It is a heterocyclic aromatic compound containing a pyrazole ring and a benzoic acid moiety. 4-(1H-Pyrazol-1-yl)benzoic acid is used in the synthesis of pharmaceuticals and agrochemicals. It has been studied for its potential biological activities, including anti-inflammatory and anticancer properties. Additionally, it has been utilized as a building block in the preparation of diverse organic compounds. Its structure and properties make it a versatile and important chemical in various scientific fields.

InChI:InChI=1/C10H8N2O2/c13-10(14)8-2-4-9(5-3-8)12-7-1-6-11-12/h1-7H,(H,13,14)/p-1

Upstream product

• 25699-83-6 4-pyrazol-1-yl-benzonitrile 
• 1194-02-1 4-fluorobenzonitrile 
• 400750-29-0 methyl 4-(1H-pyrazol-1-yI)benzenecarboxylate 
• 403-33-8 methyl 4-flurobenzoate 

Downstream Products

• 1087329-22-3 (R)-tert-butyl 3-(N-methyl-4-(1H-pyrazol-1-yl)benzamido)-pyrrolidine-1-carboxylate 
• 1087329-24-5 N-methyl-4-(1H-pyrazol-1-yl)-N-[(3R)-pyrrolidin-3-yl]benzamide 
• 1087329-20-1 (R)-tert-butyl 3-(4-(1H-pyrazol-1-yl)benzamido)pyrrolidine-1-carboxylate 
• 1353548-25-0 [(Sn(n-Bu)2)4(4-pyrazolylbenzoate)2O₂(MeO)2] 
• 220461-83-6 4-(1H-pyrazol-1-yl)benzoyl chloride 
• 143426-47-5 4-pyrazol-1-yl-benzoic acid ethyl ester 

Relevant articles and documents

Diphenyl ether-containing 4-(1H-pyrazol-1-yl)biphenylformamide compounds and applications

The present invention discloses diphenyl ether-containing 4- (1H- pyrazol-1-yl) biphenylformamide compounds and applications, the structural formula is: wherein the R group is: 4-H, 4-Cl, 2-Cl and4-OCH3 of one. The application of diphenyl ether

PYRROLOTRIAZINONES AND IMIDAZOTRIAZINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS

The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, R6, X1, X2, m, and n are described herein.

AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS

The present invention provides a compound of formula I and the use thereof for the treatment of a central nervous system disorder related to or affected by the histamine-3 receptor