1621-70-1Relevant academic research and scientific papers
Synthesis and evaluation of novel carbamate-substituted flavanone derivatives as potent acetylcholinesterase inhibitors and anti-amnestic agents
Anand, Preet,Singh, Baldev
, p. 1648 - 1659 (2013/07/26)
This study was designed to synthesize and evaluate flavanone derivatives with phenylcarbamate moiety as potent acetylcholinesterase (AChE) inhibitors and anti-amnestic agents for management of AD. The synthesis of carbamate-substituted flavanone derivativ
Aromatic ring hydroxylation of flavanones by dimethyldioxirane
Bernini, Roberta,Mincione, Enrico,Sanetti, Anna,Mezzetti, Maurizio,Bovicelli, Paolo
, p. 1087 - 1090 (2007/10/03)
The selective and efficient oxidation of flavanones with dimethyldioxirane (DMD) is reported. Aromatic rings carrying methoxy groups were selectively hydroxylated in neutral and acidic media. In the latter case inversion of chemoselectivity with respect to the benzylethereal position was observed. This behaviour was exploited to obtain polyhydroxylated flavanones, which are compounds with potential antioxidant and biological properties. (C) 2000 Elsevier Science Ltd.
