1621090-33-2Relevant academic research and scientific papers
6-Benzyloxyquinazolin-7-ylurea derivatives with an anticancer activity
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Paragraph 0162; 0163; 0164; 0165; 0166; 0218; 0219, (2018/02/28)
The present invention relates to a 6-benzyloxyquinazoline-7-ylurea derivative having anticancer activity and, more specifically, to a 6-benzyloxyquinazoline-7-ylurea derivative represented by chemical formula 1 and a compound selected from pharmaceuticall
Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: Design, synthesis, and molecular docking study
Elkamhawy, Ahmed,Lee, Jiyoun,Park, Beoung-Geon,Park, Insun,Pae, Ae Nim,Roh, Eun Joo
, p. 466 - 475 (2014/08/05)
A novel series of twenty-six quinazoline-urea derivatives was designed and synthesized. Their blocking activities against β-amyloid peptide (Aβ) induced mitochondrial permeability transition pore (mPTP) opening were evaluated by JC-1 assay which measured
