1621188-48-4

Basic information

• Product Name: methyl 2,3,4-tri-O-benzyl-6-O-(2-deoxy-3,4-O-(1,1,3,3-tetramethyldisiloxane-1,3-diyl)-6-O-triisopropylsilyl-α-D-erythro-hexapyranosyl)-α-D-glucopyranoside
• Synonyms: methyl 2,3,4-tri-O-benzyl-6-O-(2-deoxy-3,4-O-(1,1,3,3-tetramethyldisiloxane-1,3-diyl)-6-O-triisopropylsilyl-α-D-erythro-hexapyranosyl)-α-D-glucopyranoside
• CAS NO: 1621188-48-4
• Molecular Weight: 897.339
• Mol File: 1621188-48-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,3,4-tri-O-benzyl-6-O-(2-deoxy-3,4-O-(1,1,3,3-tetramethyldisiloxane-1,3-diyl)-6-O-triisopropylsilyl-α-D-erythro-hexapyranosyl)-α-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3,4-tri-O-benzyl-6-O-(2-deoxy-3,4-O-(1,1,3,3-tetramethyldisiloxane-1,3-diyl)-6-O-triisopropylsilyl-α-D-erythro-hexapyranosyl)-α-D-glucopyranoside(1621188-48-4)
• EPA Substance Registry System: methyl 2,3,4-tri-O-benzyl-6-O-(2-deoxy-3,4-O-(1,1,3,3-tetramethyldisiloxane-1,3-diyl)-6-O-triisopropylsilyl-α-D-erythro-hexapyranosyl)-α-D-glucopyranoside(1621188-48-4)

Safety Data

• Hazardous Substances Data: 1621188-48-4(Hazardous Substances Data)

Upstream product

• 1079205-73-4 C₃₇H₅₂O₆Si 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 53008-65-4 methyl 2,3,4-tri-O-benzyl-D-glucopyranoside 
• 1621188-33-7 1,2-dideoxy-3,4-O-(1,1,3,3-tetramethyldisiloxane-1,3-diyl)-6-O-triisopropylsilyl-D-arabino-1-hexenopyranose 
• 137915-37-8 1,2-dideoxy-6-O-triisopropylsilyl-D-arabino-1-hexenopyranose 
• 13154-24-0 triisopropylsilyl chloride 
• 13265-84-4 D-glucal 

Relevant articles and documents

A 3,4-trans-fused cyclic protecting group facilitates α-selective catalytic synthesis of 2-deoxyglycosides

A practical approach has been developed to convert glucals and rhamnals into disaccharides or glycoconjugates with high α-selectivity and yields (77-97 %) using a trans-fused cyclic 3,4-O-disiloxane protecting group and TsOH·H2O (1 mol %) as a catalyst. Control of the anomeric selectivity arises from conformational locking of the intermediate oxacarbenium cation. Glucals outperform rhamnals because the C6 side-chain conformation augments the selectivity.