1621424-10-9

Basic information

• Product Name: benzyl (E)-3-ethoxyacrylate
• Synonyms: benzyl (E)-3-ethoxyacrylate
• CAS NO: 1621424-10-9
• Molecular Weight: 206.241
• Mol File: 1621424-10-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl (E)-3-ethoxyacrylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (E)-3-ethoxyacrylate(1621424-10-9)
• EPA Substance Registry System: benzyl (E)-3-ethoxyacrylate(1621424-10-9)

Safety Data

• Hazardous Substances Data: 1621424-10-9(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 14447-01-9 benzyl prop-2-ynoate 
• 140-11-4 Benzyl acetate 
• 109-94-4 formic acid ethyl ester 
• 100-51-6 benzyl alcohol 
• 6192-01-4 (E)-3-ethoxyprop-2-enoic acid 
• 100-39-0 benzyl bromide 

Downstream Products

• 72594-91-3 benzyl (E)-3-(((benzyloxy)carbonyl)amino)acrylate 

Relevant articles and documents

Metal-Free Stereoselective Synthesis of (E)- And (Z)-N-Monosubstituted β-Aminoacrylates via Condensation Reactions of Carbamates

N-monosubstituted β-aminoacrylates are building blocks, which have been used in the preparation of amino acids and pharmaceuticals. Two efficient, stereoselective methods of preparation, via acid- or base-promoted condensation reactions of carbamates, are described. The base-promoted reaction is E-selective, while acid catalysis can, through the choice of solvent, selectively form E or Z. The acid-catalyzed E-selective process proceeds through a crystallization obviating the need for chromatographic purification.

Platinum- and gold-catalyzed hydroalkoxylation and tetramerization of propiolate esters

PtCl2 was found to efficiently catalyze intermolecular additions of propiolate esters with alcohols. The reaction of propiolate esters and alcohols in the presence of PtCl2 gave (E)-vinyl ethers as the major products at 60 °C, whereas alkyl 3,3-dialkoxypropanoates were predominantly obtained when the reaction temperature was set to 80°C. On the other hand, a novel regioselective tetramerization of propiolate esters catalyzed by AuCl3 under mild conditions afforded 1,2,5,6-tetrasubstituted- cyclooctatetraene (1,2,5,6-COT) in moderate yields.