1621595-85-4

Basic information

• Product Name: 1-(4-cyanophenyl)-7-phenyl-1,7-dicarba-closo-dodecaborane
• Synonyms: 1-(4-cyanophenyl)-7-phenyl-1,7-dicarba-closo-dodecaborane
• CAS NO: 1621595-85-4
• Molecular Weight: 321.433
• Mol File: 1621595-85-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-cyanophenyl)-7-phenyl-1,7-dicarba-closo-dodecaborane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-cyanophenyl)-7-phenyl-1,7-dicarba-closo-dodecaborane(1621595-85-4)
• EPA Substance Registry System: 1-(4-cyanophenyl)-7-phenyl-1,7-dicarba-closo-dodecaborane(1621595-85-4)

Safety Data

• Hazardous Substances Data: 1621595-85-4(Hazardous Substances Data)

Upstream product

• 16351-47-6 1-phenyl-1,7-dicarba-closo-dodecaborane⁽¹²⁾ 
• 3058-39-7 4-iodobenzonitrile 

Downstream Products

• 1621595-87-6 1-(4-cyanophenyl)-7-(3-nitrophenyl)-1,7-dicarba-closo-dodecaborane 
• 1621595-89-8 1-(4-cyanophenyl)-7-(4-nitrophenyl)-1,7-dicarba-closo-dodecaborane 

Relevant articles and documents

Design and synthesis of nonsteroidal progesterone receptor antagonists based on C,C′-diphenylcarborane scaffold as a hydrophobic pharmacophore

The progesterone receptor (PR) plays important roles in multiple physiological processes, including female reproduction. Here, we report the synthesis of nonsteroidal PR antagonists containing a boron cluster as the hydrophobic core. We found that 1,7-diphenyl-meta-carborane was the preferred substructure among the three carborane isomers. Compound 39 was the most potent PR antagonist (IC50: 29 nM). Compound 41 also exhibited potent activity (IC50: 93 nM), and did not bind to androgen receptor, glucocorticoid receptor or mineralocorticoid receptor. These compounds may be useful for investigating potential clinical applications of PR modulators.