1621652-17-2

Basic information

• Product Name: 3-(4-chlorophenyl)-2-hydroperoxy-2-methylpropanenitrile
• Synonyms: 3-(4-chlorophenyl)-2-hydroperoxy-2-methylpropanenitrile
• CAS NO: 1621652-17-2
• Molecular Weight: 211.648
• Mol File: 1621652-17-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-chlorophenyl)-2-hydroperoxy-2-methylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-2-hydroperoxy-2-methylpropanenitrile(1621652-17-2)
• EPA Substance Registry System: 3-(4-chlorophenyl)-2-hydroperoxy-2-methylpropanenitrile(1621652-17-2)

Safety Data

• Hazardous Substances Data: 1621652-17-2(Hazardous Substances Data)

Upstream product

• 1073-69-4 N-4-chlorophenylhydrazine 
• 126-98-7 methacrylonitrile 

Relevant articles and documents

Manganese(IV)-mediated hydroperoxyarylation of alkenes with aryl hydrazines and dioxygen from air

We report a new carbooxygenation-type version of the Meerwein arylation in which the introduction of oxygen is achieved by using dioxygen from the air. In this way, hydroperoxides were obtained from activated as well as non-activated alkenes by oxidizing aryl hydrazines with manganese dioxide. The best results were obtained with α-substituted acrylates. Importantly, the aryl hydrazine has to be added slowly to the reaction mixture to allow sufficient uptake of dioxygen from the air. Competition and labeling experiments revealed hydroperoxyl radicals as novel oxygen-centered radical scavengers. The introduction of oxygen into a Meerwein arylation has been achieved with dioxygen from air as an oxygen-centered radical scavenger. The slow addition of the aryl hydrazine is key to aryl radical formation through oxidation with manganese dioxide; whereby, hydroperoxides were obtained from activated as well as non-activated alkenes.