162191-09-5Relevant articles and documents
Substrate specificity of 2-deoxy-scyllo-inosose synthase, the starter enzyme for 2-deoxystreptamine biosynthesis, toward deoxyglucose-6-phosphates and proposed mechanism.
Iwase,Kudo,Yamauchi,Kakinuma
, p. 2396 - 2407 (2007/10/03)
A crucial enzyme in the biosynthesis of the 2-deoxystreptamine aglycon of clinically important aminocyclitol antibiotics is 2-deoxy-scyllo-inosose synthase (DOIS), which is responsible for the initial carbocycle formation of 2-deoxy-scyllo-inosose (1) fro
NUCLEOPHILIC SUBSTITUTION VERSUS RADICAL REACTION FOR CARBOHYDRATES DEOXYGENATION: APPLICATION AT C-4 OF METHYL-α-D-GLUCOPYRANOSIDE DERIVATIVES
Czernecki, Stanislas,Horns, Stefan,Valery, Jean-Marc
, p. 157 - 164 (2007/10/02)
Two methods for deoxygenation at C-4 of methyl 2,3-di-O-benzyl-α-D-glucopyranoside are reported.The first one involves nucleophilic displacement of a secondary methane sulfonate by lithium triethylborohydride to afford methyl 2,3-di-O-benzyl-4-deoxy-α-D-x