1621967-91-6

Basic information

• Product Name: 3-(4-methoxyphenyl)-2-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one
• Synonyms: 3-(4-methoxyphenyl)-2-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one
• CAS NO: 1621967-91-6
• Molecular Weight: 348.425
• Mol File: 1621967-91-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)-2-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-2-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one(1621967-91-6)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-2-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one(1621967-91-6)

Safety Data

• Hazardous Substances Data: 1621967-91-6(Hazardous Substances Data)

Upstream product

• 82437-64-7 methyl 3-amino-4-phenyl-2-thiophenecarboxylate 
• 140-29-4 phenylacetonitrile 
• 22252-92-2 3-hydroxy-2-phenylacrylonitrile 
• 1621968-37-3 3-amino-N-(4-methoxyphenyl)-4-phenylthiophene-2-carboxamide 
• 73591-08-9 3-methoxy-2-phenylacrylonitrile 

Relevant articles and documents

THIENOPYRIMIDINONE DERIVATIVES AS mGluR1 ANTAGONISTS

Disclosed are thienopyrimidinone derivatives as antagonists that act on metabotropic glutamate receptor subtype 1. The thienopyrimidinone derivatives show pharmacological activity against metabotropic glutamate receptor-related diseases, including pain, such as neuropathic pain and migraine, psychiatric diseases, such as anxiety disorder and schizophrenia, urinary incontinence, and neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. Also disclosed are methods for preparing the thienopyrimidinone derivatives, and pharmaceutical compositions containing the thienopyrimidinone derivatives as active ingredients.