22252-92-2Relevant articles and documents
Synthesis and seed germination stimulating activity of some imino analogs of strigolactones
Kondo, Yuki,Tadokoro, Eriko,Matsuura, Mayuko,Iwasaki, Kyoko,Sugimoto, Yukihiro,Miyake, Hideyoshi,Takikawa, Hirosato,Sasaki, Mitsuru
, p. 2781 - 2786 (2007)
Strigolactones are germination stimulants for seeds of the root parasitic weeds, Striga and Orobanche spp. The imino analog of GR24 showed moderate germination stimulating activity against the seeds of S. hermonthica. The seed germination stimulating activity of some phenyliminoacetates and phenyliminoacetonitriles was also examined. The degree of activity of the phenyliminoacetate was less than that of the phenylacrylates. On the other hand, the degree of activity of the phenyliminoacetonitrile was comparable to that of the phenylacrylonitriles. Among the tested compounds, the 3- pyridyliminoacetonitrile showed higher activity against the seeds of O. crenata than GR24. These findings demonstrate that it is not always essential to have the Michael acceptor of the C-D ring junction moiety which has been proposed to react with nucleophilic species presented at the target site to enhance the activity.
THIENOPYRIMIDINONE DERIVATIVES AS mGluR1 ANTAGONISTS
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Paragraph 0193; 0194, (2014/08/19)
Disclosed are thienopyrimidinone derivatives as antagonists that act on metabotropic glutamate receptor subtype 1. The thienopyrimidinone derivatives show pharmacological activity against metabotropic glutamate receptor-related diseases, including pain, such as neuropathic pain and migraine, psychiatric diseases, such as anxiety disorder and schizophrenia, urinary incontinence, and neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. Also disclosed are methods for preparing the thienopyrimidinone derivatives, and pharmaceutical compositions containing the thienopyrimidinone derivatives as active ingredients.
α-CYANO-β-STYRENYL ESTERS FOR AMIDE BOND FORMATION
Roose, B.,Anteunis, M. J. O.,Tavernier, D.
, p. 267 - 270 (2007/10/02)
p-X-α-cyano-β-styrenyl esters (X = H, Cl, CF3, NO2) of N-benzyloxycarbonyl valine were prepared.The rate constant for amide formation with methyl valinate was assayed; it increases with increasing electron attracting power of the para substituent.The N-hydroxysuccinimidoyl ester and the p-H-α-cyano-β-styrenyl ester of valine have comparable reactivities.
